Ebpay生命医药出版社

    • Ebpay生命

    100763

    论文已发表

    提 交 论 文


    注册即可获取Ebpay生命的最新动态

    注 册



    IF 收录期刊



    • 3.3 Breast Cancer (Dove Med Press)
    • 3.4 Clin Epidemiol
    • 2.5 Cancer Manag Res
    • 2.9 Infect Drug Resist
    • 3.5 Clin Interv Aging
    • 4.7 Drug Des Dev Ther
    • 2.7 Int J Chronic Obstr
    • 6.6 Int J Nanomed
    • 2.5 Int J Women's Health
    • 2.5 Neuropsych Dis Treat
    • 2.7 OncoTargets Ther
    • 2.0 Patient Prefer Adher
    • 2.3 Ther Clin Risk Manag
    • 2.5 J Pain Res
    • 2.8 Diabet Metab Synd Ob
    • 2.8 Psychol Res Behav Ma
    • 3.0 Nat Sci Sleep
    • 1.8 Pharmgenomics Pers Med
    • 2.7 Risk Manag Healthc Policy
    • 4.2 J Inflamm Res
    • 2.1 Int J Gen Med
    • 4.2 J Hepatocell Carcinoma
    • 3.7 J Asthma Allergy
    • 1.9 Clin Cosmet Investig Dermatol
    • 2.7 J Multidiscip Healthc



    更多详情 >>





    视频

    LDH-A  顺利获得上调 ZEB2 促进肠型胃癌上皮间质转化

     

    Authors Zhang Y, Lin S, Chen Y, Yang F, Liu S

    Received 24 January 2018

    Accepted for publication 11 March 2018

    Published 27 April 2018 Volume 2018:11 Pages 2363—2373

    DOI http://doi.org/10.2147/OTT.S163570

    Checked for plagiarism Yes

    Review by Single-blind

    Peer reviewers approved by Dr Andrew Yee

    Peer reviewer comments 2

    Editor who approved publication: Prof. Dr. Geoffrey Pietersz

    简介：浸润和转移是胃癌复发和死亡的重要原因。顺利获得体外研究发现乳酸脱氢酶 A (LDH-A) 顺利获得上调 ZEB2 促进肠型胃癌细胞浸润和转移。LDH-A  和 ZEB2 密切相关性在 371 例肠型胃癌组织标本中的到证实。生存分析结果显示： LDH-A 和 ZEB2 联合表达患者预后更差。因此，LDH-A  和 ZEB2 的相关性可能为肠型胃癌给予治疗策略。
    Keywords: intestinal-type gastric cancer, LDH-A, ZEB2, epithelial–mesenchymal transition, Warburg effect, glycolysis


     

    摘要视频链接：Lactate dehydrogenase A




    Download Article[PDF]