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已发表论文

调整钛合金种植体的钛涂层表面金相组织以增强种植体的生物活性

 

Authors Wang H, Lai YK, Zheng RY, Bian Y, Zhang KQ, Lin CJ

Published Date June 2015 Volume 2015:10 Pages 3887—3896

DOI http://dx.doi.org/10.2147/IJN.S75999

Received 17 October 2014, Accepted 3 February 2015, Published 8 June 2015

Approved for publication by Dr Lei Yang

Abstract: Biological performance of artificial implant materials is closely related to their surface characteristics, such as microtopography, and composition. Therefore, convenient fabrication of artificial implant materials with a cell-friendly surface structure and suitable composition was of great significance for current tissue engineering. In this work, titanate materials with a nanotubular structure were successfully fabricated through a simple chemical treatment. Immersion test in a simulated body fluid and in vitro cell culture were used to evaluate the biological performance of the treated samples. The results demonstrate that the titanate layer with a nanotubular structure on Ti substrates can promote the apatite-inducing ability remarkably and greatly enhance cellular responses. This highlights the potential of such titanate biomaterials with the special nanoscale structure and effective surface composition for biomedical applications such as bone implants.
Keywords: nanotubes structure, bone-like apatite, cell culture, biological performance






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